Title of article
FANCF methylation contributes to chemoselectivity in ovarian cancer
Author/Authors
Olopade، نويسنده , , Olufunmilayo I and Wei، نويسنده , , Minjie، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
417
To page
420
Abstract
A new model of ovarian cancer tumor progression implicates aberrant FANCF promoter methylation that is associated with gene silencing and disruption of the Fanconi-anemia-BRCA pathway. Disruption of the pathway occurs de novo in ovarian cancers and may contribute to selective sensitivity to platinum salts.
Journal title
Cancer Cell
Serial Year
2003
Journal title
Cancer Cell
Record number
1335010
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