Title of article
A Brake Becomes an Accelerator: PTP1B—A New Therapeutic Target for Breast Cancer
Author/Authors
Tonks، نويسنده , , Nicholas K. and Muthuswamy، نويسنده , , Senthil K.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
3
From page
214
To page
216
Abstract
The protein tyrosine phosphatase PTP1B, previously recognized for its role in downregulating insulin and leptin signaling, has now been shown to function as a positive regulator of signaling events associated with breast tumorigenesis. Inhibitors of PTP1B that have been developed as drug candidates for treatment of diabetes and obesity may offer new avenues for the treatment of breast cancer.
Journal title
Cancer Cell
Serial Year
2007
Journal title
Cancer Cell
Record number
1336426
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