Author/Authors :
Freie، نويسنده , , Brian W. and Eisenman، نويسنده , , Robert N.، نويسنده ,
Abstract :
In this issue of Cancer Cell, Murphy et al. describe a mouse model designed to examine the biological effects of different levels of deregulated c-myc expression. They provide evidence that distinct threshold levels of Myc are required for increased proliferation and for apoptosis in different tissues.