Title of article
Unholy Matrimony: Aurora A and N-Myc as Malignant Partners in Neuroblastoma
Author/Authors
Maris، نويسنده , , John M.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2009
Pages
2
From page
5
To page
6
Abstract
Aurora A is a mitotic kinase that is essential for regulation of the G2/M checkpoint. In this issue of Cancer Cell, Otto et al. report that Aurora A interacts with MYCN, a potent oncogene in human neuroblastoma, and sequesters it from proteolytic degradation. This surprising finding further enhances Aurora Aʹs potential as a therapeutic target.
Journal title
Cancer Cell
Serial Year
2009
Journal title
Cancer Cell
Record number
1336901
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