• Title of article

    SUMO Boosts the DNA Damage Response Barrier against Cancer

  • Author/Authors

    Bartek، نويسنده , , Jiri and Hodny، نويسنده , , Zdenek، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2010
  • Pages
    3
  • From page
    9
  • To page
    11
  • Abstract
    Cells exposed to genotoxic insults such as ionizing radiation activate a signaling cascade to repair the damaged DNA. Two recent articles published in Nature show that such genome maintenance requires modifications of tumor suppressor proteins BRCA1 and 53BP1 by the small ubiquitin-like modifier SUMO.
  • Journal title
    Cancer Cell
  • Serial Year
    2010
  • Journal title
    Cancer Cell
  • Record number

    1337013

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1337013