Title of article
IDH1 and IDH2: Not Your Typical Oncogenes
Author/Authors
Reitman، نويسنده , , Zachary J. and Parsons، نويسنده , , D. Williams and Yan، نويسنده , , Hai، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2010
Pages
2
From page
215
To page
216
Abstract
Oncogenes usually increase their normal function when activated. However, seemingly oncogenic mutations in IDH1 and IDH2 reduce their native enzyme activity. In this issue of Cancer Cell, Ward et al. pin down a neomorphic enzyme activity as a possible oncogenic function for these alterations.
Journal title
Cancer Cell
Serial Year
2010
Journal title
Cancer Cell
Record number
1337051
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