• Title of article

    IDH1 and IDH2: Not Your Typical Oncogenes

  • Author/Authors

    Reitman، نويسنده , , Zachary J. and Parsons، نويسنده , , D. Williams and Yan، نويسنده , , Hai، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2010
  • Pages
    2
  • From page
    215
  • To page
    216
  • Abstract
    Oncogenes usually increase their normal function when activated. However, seemingly oncogenic mutations in IDH1 and IDH2 reduce their native enzyme activity. In this issue of Cancer Cell, Ward et al. pin down a neomorphic enzyme activity as a possible oncogenic function for these alterations.
  • Journal title
    Cancer Cell
  • Serial Year
    2010
  • Journal title
    Cancer Cell
  • Record number

    1337051