• Title of article

    Loss of 53BP1 Is a Gain for BRCA1 Mutant Cells

  • Author/Authors

    Kass، نويسنده , , Elizabeth M. and Moynahan، نويسنده , , Mary Ellen and Jasin، نويسنده , , Maria، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2010
  • Pages
    3
  • From page
    423
  • To page
    425
  • Abstract
    Mutations in BRCA1 predispose to tumorigenesis presumably from the inability to accurately repair DNA double-strand breaks by homologous recombination. Two new papers shed light on how loss of the DNA damage response protein 53BP1 reverses phenotypes of BRCA1 mutant cells, with potential clinical implications.
  • Journal title
    Cancer Cell
  • Serial Year
    2010
  • Journal title
    Cancer Cell
  • Record number

    1337114

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1337114