• Title of article

    MEKing Retinoids Work Better

  • Author/Authors

    Mossé، نويسنده , , Yaël P. and Maris، نويسنده , , John M.، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2010
  • Pages
    3
  • From page
    103
  • To page
    105
  • Abstract
    Retinoids can induce terminal differentiation in a subset of neuronal cancer cells, but what determines response has been unclear. In a recent issue of Cell, Hِlzel and colleagues show that hyperactive RAS signaling imparts retinoid resistance to neuroblastoma cells, which can be reversed by inhibiting MAPK, suggesting new therapeutic opportunities.
  • Journal title
    Cancer Cell
  • Serial Year
    2010
  • Journal title
    Cancer Cell
  • Record number

    1337205

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1337205