• Title of article

    BRAF Inhibitor Unveils Its Potential against Advanced Melanoma

  • Author/Authors

    Vultur، نويسنده , , Adina and Villanueva، نويسنده , , Jessie and Herlyn، نويسنده , , Meenhard، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2010
  • Pages
    2
  • From page
    301
  • To page
    302
  • Abstract
    Summary onsiveness to therapy is a hallmark feature of advanced metastatic melanoma. However, the discovery of BRAF-activating mutations in approximately 50% of human melanomas has provided an attractive therapeutic target. Here, we discuss two recent publications focusing on the mutant BRAF kinase inhibitor PLX4032 that validate oncogene-targeted melanoma therapy.
  • Journal title
    Cancer Cell
  • Serial Year
    2010
  • Journal title
    Cancer Cell
  • Record number

    1337251