Title of article
BRAF Inhibitor Unveils Its Potential against Advanced Melanoma
Author/Authors
Vultur، نويسنده , , Adina and Villanueva، نويسنده , , Jessie and Herlyn، نويسنده , , Meenhard، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2010
Pages
2
From page
301
To page
302
Abstract
Summary
onsiveness to therapy is a hallmark feature of advanced metastatic melanoma. However, the discovery of BRAF-activating mutations in approximately 50% of human melanomas has provided an attractive therapeutic target. Here, we discuss two recent publications focusing on the mutant BRAF kinase inhibitor PLX4032 that validate oncogene-targeted melanoma therapy.
Journal title
Cancer Cell
Serial Year
2010
Journal title
Cancer Cell
Record number
1337251
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