• Title of article

    Unfavorable Drug Interactions in Targeted Breast Cancer Therapy

  • Author/Authors

    Groner، نويسنده , , Bernd and Hynes، نويسنده , , Nancy E.، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2010
  • Pages
    2
  • From page
    401
  • To page
    402
  • Abstract
    Trastuzumab is used to treat HER2-positive breast cancer; erythropoietin (EPO) is used to alleviate chemotherapy-associated side effects. In this issue of Cancer Cell, Liang et al. show that many breast tumors express EPO receptor (EpoR), whose activation by EPO recovers signaling pathways downregulated by trastuzumab, thereby blunting trastuzumabʹs therapeutic effect.
  • Journal title
    Cancer Cell
  • Serial Year
    2010
  • Journal title
    Cancer Cell
  • Record number

    1337270

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1337270