Author/Authors :
Tao، نويسنده , , Jianning and Erez، نويسنده , , Ayelet and Lee، نويسنده , , Brendan، نويسنده ,
Abstract :
The outgrowth of metastatic cells to bone depends on the interaction between multiple intrinsic and host factors. In this issue of Cancer Cell, Sethi and colleagues report Notch signaling in bone cells as responsible for promoting this outgrowth and provide evidence for a beneficial treatment effect of NOTCH inhibitors.