• Title of article

    Beyond Hormone Therapy for Prostate Cancer with PARP inhibitors

  • Author/Authors

    Sebastian de Bono، نويسنده , , Johann and Sandhu، نويسنده , , Shahneen and Attard، نويسنده , , Gerhardt، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2011
  • Pages
    2
  • From page
    573
  • To page
    574
  • Abstract
    In this issue of Cancer Cell, Brenner et al. describe that the poly-(ADP) ribose polymerase (PARP) may mediate ERG function and that PARP blockade has antitumor activity in ETS gene-rearranged prostate cancer models. These data support the clinical evaluation of PARP inhibitors for treating ETS gene-rearranged prostate cancers.
  • Journal title
    Cancer Cell
  • Serial Year
    2011
  • Journal title
    Cancer Cell
  • Record number

    1337487