Author/Authors :
Matei، نويسنده , , Irina and Ghajar، نويسنده , , Cyrus M. and Lyden، نويسنده , , David، نويسنده ,
Abstract :
In the July issue of Nature Medicine, Massagué and colleagues define a biphasic role for the extracellular matrix protein tenascin C as a metastatic niche component in lung colonization by breast cancer cells. These results provide a rationale for designing therapies targeting metastatic progression by disrupting its very foundations.