Title of article
PI3King on MYCN to Improve Neuroblastoma Therapeutics
Author/Authors
Hogarty، نويسنده , , Michael D. and Maris، نويسنده , , John M.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2012
Pages
3
From page
145
To page
147
Abstract
MYCN is an oncogenic driver of childhood neuroblastoma, a frequently lethal pediatric tumor. In a recent paper in Science Translational Medicine, Chanthery and colleagues demonstrate that PI3K inhibition leads to the dual therapeutic benefits of enhanced MYCN degradation and loss of a paracrine angiogenic signal mediated by MYCN.
Journal title
Cancer Cell
Serial Year
2012
Journal title
Cancer Cell
Record number
1337789
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