Author/Authors :
King، نويسنده , , Bryan and Ntziachristos، نويسنده , , Panagiotis and Aifantis، نويسنده , , Iannis، نويسنده ,
Abstract :
TLX1 and TLX3 are two closely-related homeobox transcriptional repressors frequently misexpressed and translocated in T cell acute lymphoblastic leukemia (T-ALL). In this issue of Cancer Cell, Dadi et al. provide new insights into how these factors are recruited by ETS-1 to the TCRα enhancer and actively repress differentiation.
