Title of article :
A Big Step for SIRT7, One Giant Leap for Sirtuins… in Cancer
Author/Authors :
Martيnez-Redondo، نويسنده , , Paloma and Santos-Barriopedro، نويسنده , , Irene and Vaquero، نويسنده , , Alejandro، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2012
Abstract :
Recently reporting in Nature, Barber et al. demonstrated that SIRT7 maintains critical features that define cancer cells by removing the acetylation mark on lysine 18 of histone H3. Interestingly, hypoacetylation of H3K18 has been described as a general marker of tumor prognosis and oncoviral transformation.
Journal title :
Cancer Cell
Journal title :
Cancer Cell