• Title of article

    To the Rescue: The Fanconi Anemia Genome Stability Pathway Salvages Replication Forks

  • Author/Authors

    Moldovan، نويسنده , , George-Lucian and DʹAndrea، نويسنده , , Alan D.، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2012
  • Pages
    2
  • From page
    5
  • To page
    6
  • Abstract
    DNA damage can arrest replication forks during S phase. Failure to stabilize and restart arrested forks results in fork collapse and genomic instability. In this issue of Cancer Cell, Schlacher et al. show that the Fanconi anemia and BRCA2 tumor suppressor pathways cooperate to protect stalled replication forks from degradation.
  • Journal title
    Cancer Cell
  • Serial Year
    2012
  • Journal title
    Cancer Cell
  • Record number

    1337945