Evaluation of the Correlation between Systemic Arterial O2 Saturation and Severity of Anemia and Cardiac Function in Cyanotic Congenital Heart Disease

Background: It is shown that about 10% of all congenital heart disease patients suffer from cyanosis and though maintaining their functional capacity and physical capabilities up to their thirties, they will face significant decreases in functional capacity and quality of life as the symptoms progress and ill consequences appear.3 Many of these patients reach adulthood with the help of palliative surgeries but drop in O2 saturation and cyanosis gradually ensues and progresses as the patients get older and the shunts become non-compliant. Method and Materials: one hundred two patients with CCD entered in the cross sectional study. Clinical and paraclinical data extract from medical files: complete blood cells, red cells indexes, serum iron, ferritin, transferrin saturation, echocardiography report, left and right ventricles ejection fraction, CKMB and troponin I . The relationship between these data and O2 saturation was evaluated. Results: 43 (42.2%) patients were female and 59 (57.8%) were male. Mean of age was 24.6±6.5 years. Mean of O2 saturation was 76.8±10.2 percent. Coefficient relationship between left ventricle EF and O2 saturation was 0.281 (P=0.017), hemoglobin and O2 saturation was - 0.293 (P=0.008), MCV and O2 saturation was 0.255 (P=0.022), MCH and O2 saturation was 0.0388, ferritin and O2 saturation was 0.326 (p=0.007), serum iron and O2 saturation was 0.270 (P=0.026), TIBC and O2 saturation was -0.288 (P=0.022), Transferrin Saturation and O2 saturation was 0.329 (P=0.001) and CKMB and O2 saturation was 0.285 (P=0.025). Conclusion: O2 saturation has significant relationship with heart function and anemia indexes in CCD patients. O2 saturation may be useful for screening of the heart function and the anemic indexes in these patients