Author/Authors :
Roushan، Nader نويسنده Assistant Professor, Department of Internal Medicine, Division of gastroenterology, Imam Khomeini hospital , , Zali، Fateme نويسنده Resident of Gastroenterology, Imam Khomeini Hospital, Department of Internal Medicine, Division of Gastroenterology , , Abtahi، Hamidreza نويسنده Advanced Thoracic Research Center, Pulmonary and Critical Care Department, Imam Khomeini Hospital , , Asadi، Mehrnaz نويسنده Assistant Professor, Department of Internal Medicine, Imam Khomeini Hospital , , Taslim، Reza نويسنده Assistant Professor, Department of Internal Medicine, Division of Gastroenterology , , Aletaha، Najme نويسنده Assistant Professor, Department of Internal Medicine, Division of Gastroenterology ,
Abstract :
Background: Sulfur mustard (SM) has acute and chronic effects on skin and mucosal surfaces. The aim of the study was to evaluate the frequency of esophagitis in a historical cohort of veterans who had been exposed to SM in Iran-Iraq war nearly 25 years ago.
Methods: One hundred two veterans with dyspepsia and/or heartburn underwent esophago-gastro-duodenoscopy. Of them, 52 cases had been exposed to SM and had chronic mustard lung disease. Controls included 50 veterans without SM exposure. Esophagitis was defined according to standard criteria.
Results: 81.6% of cases and 70.6% of controls had heart burn and/or regurgitation (p= 0.224). Esophagitis was seen in 40% of cases and 26.5% of controls (p= 0.155).
Conclusion: Based on our findings, SM exposure seems not to be associated with increased esophagitis.
