How many non-crystalline solids can be made from all the elements of the periodic table?

We estimate that over 2 00 000 non-crystalline solids (NCS) have already been produced in the last 6000 years of glass history. We then develop an equation to calculate how many NCS can (theoretically) be made from all the 80 useful elements of the periodic table, and conclude that, as we expected, astronomically long times would be required to experimentally synthesize, or simulate and test the properties of the vast number of NCS yet to be made. Nevertheless, because the properties of NCS depend mostly on their chemical nature rather than on their method of fabrication, and in view of today’s rapid scientific developments in computer technology and in ab-initio calculations and molecular dynamics simulations, we propose that ‘computer-made NCS’ may be a solution to probe the structure and properties of a significant fraction of the colossal number of possible compositions. Despite the fact that it would be impossible to prepare all possible compositions, one can anticipate many surprises in the future, with a plethora of new exotic NCS.