• Title of article

    Synthesis of 4-(2-Methylthiazol-4-yl)-Hexahydroquinoline and 1,4-Dihydropyrimidin Derivatives

  • Author/Authors

    Shafiee1، A. نويسنده 1Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 14176, Islamic Republic of Iran , , Foroughi Moghadam، M.J. نويسنده 1Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 14176, Islamic Republic of Iran , , Amini، M. نويسنده 1Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 14176, Islamic Republic of Iran , , Assadieskandar، A. نويسنده 1Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 14176, Islamic Republic of Iran ,

  • Issue Information
    فصلنامه با شماره پیاپی سال 2011
  • Pages
    5
  • From page
    21
  • To page
    25
  • Abstract
    A series of new hexahydroquinoline and 1,4-dihydropyrimidine derivatives were synthesized. Condensation of 2-methyl- thiazole-4-carboxaldehyde (1) with 1,3-cyclohexanedione and alkyl 3- aminocrotonate afforded 4-(2-methyl-thiazol-4-yl)-hexahydroquinoline while condensation of aldehyde (1) with benzoyl acetone and thiourea gave 1,4-dihydropyrimidine derivatives. The stereochemistry of 1,4-dihydropyrimidine derivatives were studied using 1HNMR.
  • Journal title
    Journal of Sciences
  • Serial Year
    2011
  • Journal title
    Journal of Sciences
  • Record number

    1369528

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1369528