Synthesis of substituted cyclopropanone acetals by carbometallation and its oxidative cleavage with manganese(IV) oxide and lead(IV) oxide

A variety of substituted cyclopropanone acetals were prepared by the addition of an organozinc reagent or a Grignard reagent to a substituted cyclopropenone acetal. MnO2- or PbO2-mediated oxidative ring opening reaction of the substituted cyclopropanone acetals affords β-alkoxyesters and protected β-aminoesters with high efficiency.