Ruthenium-catalyzed coupling reaction of 2,3,5-trisubstituted furans with aryl halides through C–H bond cleavages

A variety of functionalized furans were synthesized by way of a ruthenium-catalyzed coupling reaction of 2,3,5-trisubstituted furans with aryl halides through C–H bond cleavages. The feature of the reaction was facilitative preparation of furan derivatives good functional group tolerance. All reactions gave the desired products in moderate to good yields (56–89%) in the presences of [RuCl2(p-cymene)] and K2CO3 in NMP at 120 °C.