Synthesis and characterization of amide-functionalized N-heterocyclic carbene–Pd complexes

Amide-functionalized N-heterocyclic carbene (NHC) precursors such as azolium compounds have been designed and synthesized. Reaction of PdCl2(CH3CN)2 with the NHC–Ag complex derived from the azolium salt gave [(NHC)PdCl2]2 or (NHC)2PdCl2, whereas PdCl2(PPh3)2 reacted with the Ag complex to afford a mixed carbene/phosphine complex such as (NHC)(PPh3)PdCl2 together with a cationic [(NHC)(PPh3)2PdCl]+Cl− whose structure was characterized by X-ray crystallographic studies. Thus, the library of NHC–Pd complexes with a tethered amide group has been successfully expanded.