Author/Authors :
Milan D. Joksovic، نويسنده , , Violeta Markovi?، نويسنده , , Zorica D. Jurani?، نويسنده , , Tatjana Stanojkovi?، نويسنده , , Ljiljana S. Jovanovi?، نويسنده , , Ivan S. Damljanovi?، نويسنده , , Katalin Meszaros Szecsenyi، نويسنده , , Nina Todorovi?، نويسنده , , Sne?ana Trifunovi?، نويسنده , , Rastko D. Vuki?evi?، نويسنده ,
Abstract :
A series of new N-[(3-ferrocenyl-1-phenylpyrazol-4-yl)methyl] α-amino acids were prepared and characterized by a range of spectroscopic techniques and cyclic voltammetry. The in vitro antitumor activity of all synthesized compounds was investigated against cervix adenocarcinoma HeLa, melanoma Fem-x and myelogenous leukemia K562 cell lines using the MTT method. Tryptophan derivative 1l exhibited the highest cytotoxic activity in the cell growth inhibition of all three types of cell lines.
