• Title of article

    (2-Halogeno-5-pyridyl)dimethyl(oxiran-2-ylmethyl)silanes: New potential building blocks for the synthesis of silicon-containing drugs

  • Author/Authors

    Dennis Troegel، نويسنده , , FRANK MOLLER، نويسنده , , Reinhold Tacke، نويسنده ,

  • Issue Information
    دوفصلنامه با شماره پیاپی سال 2010
  • Pages
    4
  • From page
    310
  • To page
    313
  • Abstract
    (2-Fluoro-5-pyridyl)dimethyl(oxiran-2-ylmethyl)silane (1a) and (2-chloro-5-pyridyl)dimethyl(oxiran-2-ylmethyl)silane (1b) were prepared in two-step syntheses, starting from allylchlorodimethylsilane. Compounds 1a and 1b were characterized by elemental analyses and NMR studies. With the synthesis of 1a and 1b, new potential building blocks for the synthesis of silicon-containing drugs have been made accessible.
  • Keywords
    Organosilicon chemistry , Silane , Sila drugs , Epoxides
  • Journal title
    Journal of Organometallic Chemistry
  • Serial Year
    2010
  • Journal title
    Journal of Organometallic Chemistry
  • Record number

    1375090