Title of article
(2-Halogeno-5-pyridyl)dimethyl(oxiran-2-ylmethyl)silanes: New potential building blocks for the synthesis of silicon-containing drugs
Author/Authors
Dennis Troegel، نويسنده , , FRANK MOLLER، نويسنده , , Reinhold Tacke، نويسنده ,
Issue Information
دوفصلنامه با شماره پیاپی سال 2010
Pages
4
From page
310
To page
313
Abstract
(2-Fluoro-5-pyridyl)dimethyl(oxiran-2-ylmethyl)silane (1a) and (2-chloro-5-pyridyl)dimethyl(oxiran-2-ylmethyl)silane (1b) were prepared in two-step syntheses, starting from allylchlorodimethylsilane. Compounds 1a and 1b were characterized by elemental analyses and NMR studies. With the synthesis of 1a and 1b, new potential building blocks for the synthesis of silicon-containing drugs have been made accessible.
Keywords
Organosilicon chemistry , Silane , Sila drugs , Epoxides
Journal title
Journal of Organometallic Chemistry
Serial Year
2010
Journal title
Journal of Organometallic Chemistry
Record number
1375090
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