Synthesis, crystal structures and in vitro antitumor activities of some organoantimony arylhydroxamates

A series of novel organoantimony arylhydroxamates with the formulae [Ar3SbL2]−[HNEt3]+ (LH = arylhydroxamic acid; Ar = C6H5, 4-CH3C6H4, 3-CH3C6H4, 4-ClC6H4, 4-FC6H4) and (4-CH3C6H4)4SbL were synthesized and characterized by elemental analysis, IR, 1H NMR and mass spectroscopy. The crystal structures of (4-CH3C6H4)4SbL and [Ph3SbL2]−[HNEt3]+ were determined by X-ray diffraction. The in vitro antitumor activities of all compounds against three human cancer cells are reported.