Author/Authors :
Robert B. Nicewonger، نويسنده , , R. and Rammelsberg، نويسنده , , Declan A. E. Costello، نويسنده , , C.A. and Begley، نويسنده , , T.P.، نويسنده ,
Abstract :
Thiaminase I catalyzes the displacement of the thiazole moiety of thiamin by a wide variety of nucleophiles. In this paper, we demonstrate that this reaction proceeds with overall retention of stereochemistry.