Title of article
Synthesis and Calcium Channel Blocking Activity of 4-Indolyl-1,4-dihydropyridines
Author/Authors
Lavilla، نويسنده , , Rodolfo and Gotsens، نويسنده , , Teresa and Santano، نويسنده , , M.Carmen and Bosch، نويسنده , , Joan and Camins، نويسنده , , Antoni and Arnau، نويسنده , , Noemi and Escubedo، نويسنده , , Elena and Camarasa، نويسنده , , Jorge and Pallas، نويسنده , , Merce، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
10
From page
169
To page
178
Abstract
A series of indolyldihydropyridines has been designed, synthesized, and evaluated in order to show the effect of the indole moiety and the role of the methyl groups at the 2 and 6 positions of the dihydropyridine ring in the calcium channel blocking activity. The results seem to show that these groups constitute a critical structural requirement for the pharmacological action of these compounds.
Journal title
Bioorganic Chemistry: an International Journal
Serial Year
1997
Journal title
Bioorganic Chemistry: an International Journal
Record number
1385223
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