Author/Authors :
Lavilla، نويسنده , , Rodolfo and Gotsens، نويسنده , , Teresa and Santano، نويسنده , , M.Carmen and Bosch، نويسنده , , Joan and Camins، نويسنده , , Antoni and Arnau، نويسنده , , Noemi and Escubedo، نويسنده , , Elena and Camarasa، نويسنده , , Jorge and Pallas، نويسنده , , Merce، نويسنده ,
Abstract :
A series of indolyldihydropyridines has been designed, synthesized, and evaluated in order to show the effect of the indole moiety and the role of the methyl groups at the 2 and 6 positions of the dihydropyridine ring in the calcium channel blocking activity. The results seem to show that these groups constitute a critical structural requirement for the pharmacological action of these compounds.
