Title of article
Synthesis of a Biochemically Important Aldehyde, 3,4-Dihydroxyphenylacetaldehyde
Author/Authors
Li، نويسنده , , Shu Wen and Spaziano، نويسنده , , Vincent T and Burke، نويسنده , , William J، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
45
To page
50
Abstract
3,4-Dihydroxyphenylacetaldehyde (DOPAL) is an important precursor of the major brain metabolites of dopamine, 3,4-dihydroxyphenylacetic acid and 4-hydroxy-3-methoxy-phenylacetic acid. A new method for the synthesis of DOPAL from piperonal is described. We report for the first time the physical and chemical characteristics of DOPAL. Its importance for research in Parkinsonʹs disease and Alzheimerʹs disease is discussed.
Journal title
Bioorganic Chemistry: an International Journal
Serial Year
1998
Journal title
Bioorganic Chemistry: an International Journal
Record number
1385244
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