Title of article
Phosphoryl transfer by aminoglycoside 3′-phosphotransferases and manifestation of antibiotic resistance
Author/Authors
Kim، نويسنده , , Choonkeun and Mobashery، نويسنده , , Shahriar، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
10
From page
149
To page
158
Abstract
Transfer of the γ-phosphoryl group from ATP to aminoglycoside antibiotics by aminoglycoside 3′-phosphotransferases is one of the most important reactions for manifestation of bacterial resistance to this class of antibiotics. This review article surveys the latest structural and mechanistic findings with these enzymes.
Keywords
Aminoglycoside antibiotics , Antibiotic resistance , Mechanism of phosphate transfer
Journal title
Bioorganic Chemistry: an International Journal
Serial Year
2005
Journal title
Bioorganic Chemistry: an International Journal
Record number
1385810
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