Author/Authors :
Lecchi، نويسنده , , Cristina and Invernizzi، نويسنده , , Guido and Agazzi، نويسنده , , Alessandro and Ferroni، نويسنده , , Mariella and Pisani، نويسنده , , Laura Francesca and Savoini، نويسنده , , Giovanni and Ceciliani، نويسنده , , Fabrizio، نويسنده ,
Abstract :
The in vitro effects of the ω-3 polyunsaturated fatty acids (PUFAs) eicosapentanoic acid (EPA) and docosahexanoic acid (DHA) on phagocytosis and the extracellular respiratory burst in caprine monocytes were assessed. Blood monocytes incubated with increasing concentrations of EPA or DHA (25–200 μM) demonstrated increased phagocytosis compared to unexposed monocytes. Generation of reactive oxygen species (ROS) was not markedly affected in the presence of EPA and DHA, except at 200 μM, at which concentrations monocyte viability was also reduced.
Keywords :
Monocytes , Polyunsaturated fatty acids , Phagocytosis , goat , Reactive oxygen species
