Title of article
In vitro modulation of caprine monocyte immune functions by ω-3 polyunsaturated fatty acids
Author/Authors
Lecchi، نويسنده , , Cristina and Invernizzi، نويسنده , , Guido and Agazzi، نويسنده , , Alessandro and Ferroni، نويسنده , , Mariella and Pisani، نويسنده , , Laura Francesca and Savoini، نويسنده , , Giovanni and Ceciliani، نويسنده , , Fabrizio، نويسنده ,
Issue Information
فصلنامه با شماره پیاپی سال 2011
Pages
3
From page
353
To page
355
Abstract
The in vitro effects of the ω-3 polyunsaturated fatty acids (PUFAs) eicosapentanoic acid (EPA) and docosahexanoic acid (DHA) on phagocytosis and the extracellular respiratory burst in caprine monocytes were assessed. Blood monocytes incubated with increasing concentrations of EPA or DHA (25–200 μM) demonstrated increased phagocytosis compared to unexposed monocytes. Generation of reactive oxygen species (ROS) was not markedly affected in the presence of EPA and DHA, except at 200 μM, at which concentrations monocyte viability was also reduced.
Keywords
Monocytes , Polyunsaturated fatty acids , Phagocytosis , goat , Reactive oxygen species
Journal title
The Veterinary Journal
Serial Year
2011
Journal title
The Veterinary Journal
Record number
1395315
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