Author/Authors :
Miretti، M. M. نويسنده , , Silvia and Martignani، نويسنده , , Eugenio and Taulli، نويسنده , , Riccardo and Bersani، نويسنده , , Francesca and Accornero، نويسنده , , Paolo and Baratta، نويسنده , , Mario، نويسنده ,
Abstract :
The double-muscle phenotype is an inherited condition in Piedmontese cattle traced to a point mutation in the myostatin gene. To investigate the potential role of muscle-specific miRNAs in determining muscle development in cattle, this study examined the patterns of expression of microRNAs (miRNA-1) and miRNA-206 in Piedmontese and Friesian cattle according to phenotype and sex. There were no significant differences in miRNA-1 expression between different muscle phenotypes, sexes or breeds, whereas there was significantly higher expression of miRNA-206 in female Piedmontese compared with female Friesian cattle.
