Title of article :
Micromechanical cantilever-based biosensors
Author/Authors :
Raiteri، نويسنده , , Roberto and Grattarola، نويسنده , , Massimo and Butt، نويسنده , , Hans-Jürgen and Sklلdal، نويسنده , , Petr، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2001
Abstract :
The merging of silicon microfabrication techniques with surface functionalization biochemistry offers new exciting opportunities in developing microscopic biomedical analysis devices with unique characteristics. Micro-mechanical transducers for chemical and biosensing applications represent one possibility. Microcantilevers can transduce a chemical signal into a mechanical motion with high sensitivity. In this review we summarize how cantilever-based sensors can be operated, and their working principle is presented in few selected biosensing experiments which have been performed recently in our groups in the study of biotin–streptavidin and antigen–antibody interactions, and specific surface charge development of organic molecules. We also discuss the advantages of this novel technique as well as its potentials.
Keywords :
Immunosensor , Surface functionalization , Microfabrication , Cantilever , Biosensor
Journal title :
Sensors and Actuators B: Chemical
Journal title :
Sensors and Actuators B: Chemical