Author/Authors :
Darroudi، Majid نويسنده 1Nuclear Medicine Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran , , Sabouri، Zahra نويسنده 3Chemistry Department, Payame Noor University, 19395-4697 Tehran, Iran , , Kazemi Oskuee، Reza نويسنده , , Kargar، Hadi نويسنده Department of Chemistry, Faculty of Science, Payame Noor University (PNU), Ardakan, I.R. Iran , , Hosseini، Hasan Ali نويسنده Chemistry Department, Payame Noor University, 19395-4697 Tehran, Iran ,
Abstract :
Objective(s): A simple and "green" method was developed for preparing zinc oxide nanoparticles (ZnO-NPs) in aqueous starch solutions. Starch was used as a stabilizer to control of the mobility of zinc cations and then control growth of ZnO-NPs prepared via a sol-gel method. Because of the special structure of the starch, it permits termination of the particle growth.
Materials and Methods: The dried gel was calcined at different temperatures of 400, 500, 600, and 700 °C. The prepared ZnO-NPs were characterized by different techniques such as X-ray diffraction analysis (XRD), transmittance electron microscopy (TEM), and UV-Vis absorption. Results: The XRD results displayed hexagonal (wurtzite) crystalline structure for prepared ZnO nanoparticles with mean sizes below than 50 nm. In vitro cytotoxicity studies on neuro2A cells showed a dose dependent toxicity with non-toxic effect of concentration below 6 ?g/mL.
Conclusion: The results showed that starch is an eco-friendly material that can be used as a stabilizing agent in the sol-gel technique for preparing of ZnO-NPs in a large scale.
