Phase equilibria measurements and modeling of EPA and DHA ethyl esters in supercritical carbon dioxide

A high pressure, variable-volume visual cell was used to perform static measurements of phase equilibria involving carbon dioxide and two different fatty acid ethyl esters: eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) ethyl esters. Six temperatures ranging from 303.15 to 353.15 K were selected. In a second step, our data were compared with predictions obtained by two group contribution based models previously published. Both models are able to predict with quite high accuracy our data whatever the temperature.