Title of article :
Disinhibition of libido: an adverse effect of SSRI?
Author/Authors :
Greil، نويسنده , , W and Horvath، نويسنده , , A and Sassim، نويسنده , , N and Erazo، نويسنده , , N and Grohmann، نويسنده , , R، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2001
Pages :
4
From page :
225
To page :
228
Abstract :
Background: The article focuses on adverse drug reactions (ADR) to selective serotonin reuptake inhibitors (SSRI) concerning libido and sexual behaviour: cases of disinhibition of libido observed at the Psychiatric Hospital of Kilchberg near Zurich are described. Method: Within the scope of a drug safety program, the physicians of the hospital are regularly asked about severe and unexpected events under drug treatment. Results: During remission of depression, five outpatients noticed an increase of libido experienced as strange to them, i.e. preoccupation with sexual thoughts, first appearance of promiscuity, of unsafe sexual intercourse, and of excessive pursuit of pornography, respectively, during administration, change in dose or discontinuation of SSRI. Discussion: The case studies suggest that SSRI treatment might be associated with increase and disinhibition of libido. The phenomena are discussed as a ‘selective switch’ into partly manic symptomatology or an induction of mixed states with prevailing sexual symptoms.
Keywords :
Increased libido , Depressive disorder , Drug surveillance , selective serotonin reuptake inhibitor , Psychic adverse drug reaction , Mixed states
Journal title :
Journal of Affective Disorders
Serial Year :
2001
Journal title :
Journal of Affective Disorders
Record number :
1430255
Link To Document :
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