Title of article :
Acute antidepressant effects of right unilateral ultra-brief ECT: A double-blind randomised controlled trial
Author/Authors :
Mayur، نويسنده , , Prashanth and Byth، نويسنده , , Karen R. Harris، نويسنده , , Anthony، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2013
Pages :
4
From page :
426
To page :
429
Abstract :
Background ning the pulse width to 0.3 ms holds neurophysiological and clinical promise of making ECT safer by limiting cognitive side effects. However, the antidepressant effects of right ultra-brief unilateral ECT are under contention. In an acute ECT course, antidepressant equivalence of ultra-brief right unilateral ECT to the high-dose brief pulse right unilateral ECT was investigated. s ly depressed patients were randomised to 1 ms-brief pulse (n=18) or 0.3 ms ultra-brief pulse (n=17) right unilateral ECT, both at high-dose (6 times threshold stimulus dose) given thrice weekly. Depression severity was measured using the Montgomery Asberg Depression Rating Scale at baseline, after 8 treatments and after the acute course of ECT. s sion severity declined equally in both groups: F (1.27,41.97)=0.31, p=0.63. Median time in days to remission (95%CI) was in brief pulse ECT: 26 (18.6–33.4) and ultra-brief pulse ECT:28 (17.9–38.0). tion all sample study in the study increases the likelihood of type 2 error. sion ere depression, high-dose ultra-brief right unilateral ECT appears to show matching acute antidepressant response to an equally high-dose brief pulse right unilateral ECT.
Keywords :
Ultra-brief right unilateral ECT , Brief pulse right unilateral ECT , Severe depression , Antidepressant effects
Journal title :
Journal of Affective Disorders
Serial Year :
2013
Journal title :
Journal of Affective Disorders
Record number :
1435110
Link To Document :
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