Title of article
Surface plasmon resonance imaging technique for nucleic acid detection
Author/Authors
Manera، نويسنده , , M.G. and Spadavecchia، نويسنده , , J. and Leone، نويسنده , , A. and Quaranta، نويسنده , , F. and Rella، نويسنده , , R. and Dell’atti، نويسنده , , D. and Minunni، نويسنده , , M. and Mascini، نويسنده , , M. and Siciliano، نويسنده , , P.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
6
From page
82
To page
87
Abstract
Surface plasmon resonance (SPR) imaging is a promising label free method that can be used in an array format for the detection of biomolecular interactions. In this work the DNA–DNA interaction was investigated. A DNA SH-oligonucleotide sequence was immobilized onto suitable photolithography patterned gold substrates and the hybridization reaction with the complementary strand was monitored by means of changes in the optical properties of the surface. The DNA probe used in this work was specific for the 35S promoter, a marker of the presence of genetically modified organisms (GMOs).
Keywords
Biosensor , DNA , SPR imaging
Journal title
Sensors and Actuators B: Chemical
Serial Year
2008
Journal title
Sensors and Actuators B: Chemical
Record number
1435455
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