Author/Authors :
Shikida، نويسنده , , Mitsuhiro and Koyama، نويسنده , , Motoki and Nagao، نويسنده , , Nobuhiro and Imai، نويسنده , , Rentaro and Honda، نويسنده , , Hiroyuki and Okochi، نويسنده , , Mina and Tsuchiya، نويسنده , , Hiroyoshi and Sato، نويسنده , , Kazuo، نويسنده ,
Abstract :
The beads were magnetically agitated inside a droplet by changing the external magnetic-field distribution. We used both the multi-layered flat coils and the permanent magnet for keeping enough magnetic force for driving the beads and for forming a non-uniform magnetic-field. The temperature in the well solution was kept below 35 °C at the appropriate agitation drive currents by adding a heat-sink foil between the flat coils. The agitation performance was evaluated by using an enzymatic reaction. The reaction efficiency increased linearly with increasing reaction time and was more than four times higher with agitation than without agitation.