Title of article
A Hg2+ fluorescent chemosensor without interference from anions and Hg2+-imaging in living cells
Author/Authors
Fan، نويسنده , , Jiangli and Guo، نويسنده , , Kexin and Peng، نويسنده , , Xiaojun and Du، نويسنده , , Jianjun and Wang، نويسنده , , Jingyun and Sun، نويسنده , , Shiguo and Li، نويسنده , , Honglin، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2009
Pages
6
From page
191
To page
196
Abstract
A fluorescent chemosensor, B2, for Hg2+ containing a BODIPY fluorophore and carboxyl-thiol metal-bonding moieties was described. B2 exhibits selective fluorescence enhancement (123-fold) toward Hg2+ over other metal ions. Especially, the fluorescence enhancement was unaffected by anions existing in environment and organism. B2 shows high sensitivity to Hg2+ in a concentration of ppb range with detection limit of 77 nM. B2-ester, the membrane-permeable ethyl ester, is able to be hydrolyzed to B2 in vivo, and successfully applied to image intracellular Hg2+ in living cells.
Keywords
Imaging , Mercury ion , Living cells , Anions , fluorescence , Chemosensor
Journal title
Sensors and Actuators B: Chemical
Serial Year
2009
Journal title
Sensors and Actuators B: Chemical
Record number
1437794
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