Author/Authors :
Gomathi، نويسنده , , Palanisamy and Kim، نويسنده , , Min Kwan and Park، نويسنده , , Jung Je and Ragupathy، نويسنده , , Dhanusuraman and Rajendran، نويسنده , , Annamalai and Lee، نويسنده , , Soo Chool and Kim، نويسنده , , Jae Chang and Lee، نويسنده , , Sang Hak and Ghim، نويسنده , , Han Do، نويسنده ,
Abstract :
Multiwalled carbon nanotubes (MWNTs) grafted chitosan (CS) nanowire (NW) was prepared by phase separation method. Glucose oxidase (GOx) was sequentially immobilized into MWNT-CS-NW to obtain MWNT-CS-NW/GOx biosensor. Field emission scanning electron microscopy (FESEM) images of MWNT-CS-NW/GOx reveals the existence of MWNT and CS. Cyclic voltammetry and amperometry were used to evaluate the electrochemical determination of glucose. The MWNT-CS-NW/GOx biosensor shows an excellent performance for glucose at +0.34 V with a high sensitivity (5.03 μA/mM) and lower response time (3 s) in a wide concentration range of 1–10 mM (correlation coefficient of 0.9988). In addition, MWNT-CS-NW/GOx biosensor possesses better reproducibility, storage stability and there is negligible interference from other electroactive components.
Keywords :
MWNT , Biosensor , Glucose , Nanowire , Electroactivity , Biocompatibility
