Author/Authors :
Lee، نويسنده , , Sumin and Lee، نويسنده , , Jae Hong and Pradhan، نويسنده , , Tuhin and Lim، نويسنده , , Chang Su and Cho، نويسنده , , Bong Rae and Bhuniya، نويسنده , , Sankarprasad and Kim، نويسنده , , Sungtae and Kim، نويسنده , , Jong Seung، نويسنده ,
Abstract :
A naphthalimide-based water soluble Zn2+ sensor bearing polyamino carboxylate as a metal chelating moiety was synthesized and its application for the selective detection of Zn2+ ion in 100% aqueous solution is demonstrated. The newly developed fluorescent sensor exhibits selective binding affinity towards Zn2+ and pH insensitivity in biologically relevant range. Confocal fluorescent microscopy images indicate that this probe works effectively for intracellular Zn2+ imaging with high cell permeability.
Keywords :
Zinc , cell imaging , fluorescent sensor , DFT calculations
