Author/Authors :
Takeda، نويسنده , , Seiji and Hui، نويسنده , , Shu-Ping and Fukuda، نويسنده , , Keisuke and Fuda، نويسنده , , Hirotoshi and Jin، نويسنده , , Shigeki and Sakurai، نويسنده , , Toshihiro and Ishii، نويسنده , , Atsushi and Mukasa، نويسنده , , Koichi and Sueoka، نويسنده , , Kazuhisa and Chiba، نويسنده , , Hitoshi، نويسنده ,
Abstract :
Oxidized low-density lipoproteins (LDLs) play a key role in cardiovascular disease development, but no convenient measurement method is available for them. Using a carbon nanotube (CNT) electrode, we measured oxidized LDL using amperometric detection. Treating SWCNT with a mixture of acids produced a CNT dispersion that yielded nanotube-based electrodes after deposition on a gold electrode and drying. Current was monitored in the nanotube electrode before and after adding LDL or oxidization of LDL. Oxidized LDL changed the current more than 10 nA, although LDL addition induced no significant change. Our CNT electrode enables simple detection of oxidized LDL.
Keywords :
Sensor , Lipoprotein , Oxidation , Lipid , Nanotube
