Author/Authors :
Igli?، نويسنده , , Ale? and Verani?، نويسنده , , Peter and Jezernik، نويسنده , , Kristijan and Fo?nari?، نويسنده , , Miha and Kamin، نويسنده , , Boris and H?gerstrand، نويسنده , , Henry and Kralj-Igli?، نويسنده , , Veronika، نويسنده ,
Abstract :
We have studied dodecylmaltoside-induced echinocyte–spheroechincyte–spherocyte shape transformation and membrane vesiculation using transmission electron microscopy (TEM) on freeze-fracture replicas. It is indicated that spherical erythrocyte shape at higher dodecylmaltoside concentration is formed due to loss of membrane in the process where small, mostly tubular nanovesicles are released predominantly from the top of echinocyte and spheroechinocyte spicules.
Keywords :
Dodecylmaltoside , Erythrocyte membrane , Erythrocyte shape , Membrane shear energy , Nanovesicles