Title of article :
Influence of PAMAM dendrimers on human red blood cells
Author/Authors :
Doma?ski، نويسنده , , D.M. and Klajnert، نويسنده , , B. and Bryszewska، نويسنده , , M.، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
Polyamidoamine (PAMAM) dendrimers with different concentrations (1 nM–1 mM) (generations 2, 3, and 4) impact on human red blood cell morphology, and membrane integrity is studied. Erythrocyte shape changes from biconcave to echinocytic in dendrimers. Cell aggregation occurs. Polymers cause also concentration- and generation-dependent haemolysis.
Keywords :
PAMAM dendrimers , Erythrocytes , morphology , Haemolysis , TOXICITY
Journal title :
Bioelectrochemistry
Journal title :
Bioelectrochemistry