Author/Authors :
Sanchez، نويسنده , , C. and Padilla، نويسنده , , R. and Paciucci، نويسنده , , R. and Zabala، نويسنده , , J.C. and Avila، نويسنده , , J.، نويسنده ,
Abstract :
Binding of heat-shock protein (hsp70) to polymerized tubulin has been investigated by in vitro experiments. The tubulin region involved in binding to hsp70 corresponds to the carboxy-terminal residues 431-444, also involved in the association with other microtubule-associated proteins (MAPs). Additionally, the putative tubulin binding motif in the hsp70 protein contains a sequence related to the motif described for MAP1B protein.