Title of article :
Use of computational tools in the field of food safety
Author/Authors :
Piparo، نويسنده , , Elena Lo and Worth، نويسنده , , Andrew and Manibusan، نويسنده , , Mary M Yang، نويسنده , , Chihae and Schilter، نويسنده , , Benoît and Mazzatorta، نويسنده , , Paolo and Jacobs، نويسنده , , Miriam N. and Steinkellner، نويسنده , , Hans and Mohimont، نويسنده , , Luc، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2011
Pages :
9
From page :
354
To page :
362
Abstract :
In this article we give an overview of how computational methods are currently used in the field of food safety by national regulatory bodies, international advisory organisations and the food industry. Our results show that currently the majority of stakeholders in the field of food safety do not apply computational methods on a routine basis, mainly because of a lack of in-house expertise. Some organisations, however, are very experienced in their use and have developed specialised in-house approaches. Despite this variable situation, computational tools are widely perceived to be a useful tool to support regulatory assessments and decision making in the field of food safety. Recognized, however, is a widespread need to develop guidance documents and software tools that will promote and harmonise the use of computational methods, together with appropriate training.
Keywords :
Lowest Observed Adverse Effect Level (LOAEL) , Maximum Recommended Therapeutic Dose (MRTD) , Alternative method , risk assessment , Quantitative structure activity relationship (QSAR) , Structure activity relationship (SAR) , Mode of Action (MOA) , Margin of exposure (MOE) , TOXICITY , Threshold of Toxicological Concern (TTC)
Journal title :
Regulatory Toxicology and Pharmacology
Serial Year :
2011
Journal title :
Regulatory Toxicology and Pharmacology
Record number :
1489357
Link To Document :
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