Title of article
Genetic variation of FASN is associated with fatty acid composition of Hanwoo
Author/Authors
Yeon، نويسنده , , S.H. Tony Lee، نويسنده , , S.H. and Choi، نويسنده , , B.H. and Lee، نويسنده , , H.J. and Jang، نويسنده , , G.W. and Lee، نويسنده , , K.T. and Kim، نويسنده , , K.H. and Lee، نويسنده , , J.H. and Chung، نويسنده , , H.Y.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2013
Pages
6
From page
133
To page
138
Abstract
The objective of this study was to identify genetic variants in the bovine fatty acid synthase (FASN) gene and to evaluate associations with fatty acid composition from longissimus lumborum muscle using 90 purebred Hanwoo steers. Sequence alignments observed 6 genetic variants located in exons 20, 24, 32, 34, and 39, and PCR–RFLP analysis confirmed these variations. Genotypes of the g.15532A>C locus were significantly associated with Linolenic acid (C18:3), and genotypes of the g.17924G>A locus were significantly associated with Palmitic (C16:0), Palmitoleic (C16:1), Oleic (C18:1), saturated fatty acids, and unsaturated fatty acids. The analysis revealed that SFA and UFA showed significant correlations with fatty acid composition (Myristic (C14:0), Palmitic (C16:0), Stearic (C18:0), Oleic (C18:1), and Eicosenoic (C20:1) acids). Oleic acid (C18:1) was negatively correlated with Myristic (C14:0), Palmitic (C16:0), and Palmitoleic (C16:1) acids (P < 0.001).
Keywords
single nucleotide polymorphism , FASN , cattle , fatty acid composition
Journal title
Meat Science
Serial Year
2013
Journal title
Meat Science
Record number
1491034
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