Effect of efficiency improvement by injecting a sample at a lower carrier gas velocity in isothermal gas–liquid chromatography

The effect of efficiency improvement of chromatographic system by injecting a sample at a lower carrier gas velocity (in comparison with the carrier gas velocity at subsequent separation) was studied experimentally and theoretically in isothermal gas–liquid chromatography. The suggested technique is based on sample introduction in the programmed carrier gas velocity operation mode: the injection is realized at low carrier gas velocity, then the velocity is increased rapidly up to the operation value. The technique can be applied in chromatographic practice.